SS-31, also known as Elamipretide, is a mitochondria-targeted research peptide that binds directly to cardiolipin at the inner mitochondrial membrane rather than acting through a cell-surface receptor. For a full breakdown of its mechanism and research applications across cardiac, renal, and age-related mitochondrial decline models, see our SS-31 research overview. For researchers in Malaysia studying mitochondrial bioenergetics and oxidative stress, SS-31 is now accessible locally through Concept Peptides without the complications of international ordering.
Note: SS-31 supplied by Concept Peptides is a research-grade compound intended strictly for laboratory and preclinical research purposes. It is not for human consumption. Researchers requiring elamipretide for clinical or licensed medical use should approach their institutional pharmacy or a licensed pharmaceutical distributor.
What Makes SS-31 Different
Mitochondria-Targeted Delivery
Unlike peptides that signal through cell-surface receptors, SS-31 is a small, cell-permeable tetrapeptide from the Szeto-Schiller family, designed to concentrate selectively in the inner mitochondrial membrane. This structural targeting mechanism, rather than receptor pharmacology, is what defines its research profile.
Cardiolipin Stabilization
SS-31's defining biochemical activity is its high-affinity binding to cardiolipin, a phospholipid essential to mitochondrial cristae architecture and electron transport chain assembly. Research suggests this binding protects cardiolipin from oxidative damage and helps preserve the folded membrane structure associated with efficient ATP synthesis.
Reduction of Oxidative Stress
By stabilizing the mitochondrial membrane and supporting more efficient electron transport, SS-31 has been shown in preclinical models to reduce the downstream production of reactive oxygen species (ROS) — a mechanism of considerable research interest in the study of aging, chronic disease, and ischemia-reperfusion injury.
How to Buy SS-31 in Malaysia
Local vs Overseas Sourcing
SS-31 research peptide sourced from overseas typically arrives in 3–5 weeks and involves customs risk. As a Malaysia-based supplier, Concept Peptides ships SS-31 domestically with 1–3 business day delivery and no import complications. Every product is accompanied by a third-party Certificate of Analysis confirming sequence accuracy and purity.
What Format Is It Supplied In?
Concept Peptides supplies SS-31 as a lyophilised (freeze-dried) powder in sealed research vials, available in a 50mg size. Lyophilisation preserves stability and extends shelf life prior to reconstitution. It is reconstituted with BAC Water prior to use. A free BAC Water vial is included with every SS-31 order.
Purity Verification
Every product is independently tested by a third-party laboratory and a Certificate of Analysis (COA) is available upon request, confirming the amino acid sequence, molecular weight, and purity percentage by HPLC.
Frequently Asked Questions
What is SS-31 used for in research?
SS-31 is used in preclinical research to study mitochondria-targeted mechanisms, particularly cardiolipin stabilization, reduction of oxidative stress, and preservation of ATP production in models of cardiac, renal, skeletal muscle, and age-related mitochondrial decline.
How does SS-31 differ from other mitochondrial peptides?
Unlike receptor-mediated peptides, SS-31 works through a direct structural mechanism — binding cardiolipin at the inner mitochondrial membrane rather than activating a cell-surface receptor. This distinguishes it from compounds such as MOTS-c, which is thought to act through cellular stress-response and metabolic signalling pathways rather than direct membrane binding. See our MOTS-c research overview for a closer look at that mechanism.
Where can I buy SS-31 in Malaysia?
Research-grade SS-31 is not sold in pharmacies or retail stores in Malaysia. Concept Peptides is a Malaysia-based supplier stocking SS-31 in lyophilised research-grade format, with local payment methods and domestic shipping throughout Malaysia — order via WhatsApp or through the product page directly.
Is SS-31 available in Malaysia?
Yes — Concept Peptides stocks SS-31 in lyophilised research-grade format, available for order with local payment methods and domestic shipping throughout Malaysia, strictly for research and laboratory use.
How should it be stored after arrival?
Lyophilised SS-31 should be stored at -20°C for long-term stability. If the vial will be used within 4–6 weeks, storage at 2–8°C is acceptable. Once reconstituted with BAC water, use within 28 days and avoid repeated freeze-thaw cycles.
References
- Szeto HH. "First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics." British Journal of Pharmacology. 2014.
- Birk AV, Liu S, Soong Y, et al. "The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin." Journal of the American Society of Nephrology. 2013.